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New Clue To Heart Failure
26 April 2012

Professor Kinya Otsu, of the Centre of Research Excellence at Kings College, University of London, has made an important discovery about heart failure.
In particular about  inflammation, which creates a problematic build-up of immune cells in the heart that play a key role in heart failure.

His team has shown that a build-up of these problematic immune cells can actually be caused by our body's own DNA. The culprit DNA comes from structures in heart cells called mitochondria, which produce the energy the heart needs to pump.
When the heart is under stress, such as during heart failure, this DNA can escape from the mitochondria into the main body of heart cells.   Once escaped, it can cause immune cells to gather in the heart, making heart failure worse.
 
The discovery points towards possible new future treatments for those of us who suffer from heart failure.

Source: Nature  ;   BHF

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