- ACE Inhibitors

Angiotensin converting enzyme inhibitors

ACE inhibitors are a cornerstone of treatment for Heart Failure.   These tablets have been thoroughly researched over many years, they are proven to slow the progression of Heart Failure and make you feel better.   They have a valuable role to play in all grades of Heart Failure.

Many Heart Failure patients are on these tablets as long as there are no contra-indications (medical reasons why the medication is not suitable for you).

The ACE Inhibitors most commonly used are known as
• Perindopril
• Ramipril
• Enalapril
• Lisinopril
• Captopril

This tablet works on the rennin angiotensin aldosterone system in the kidneys by reducing the levels of a chemical in the blood called angiotensin.
Less angiotensinallows blood vessels to relax and the heart to pump more easily.   It also prevents enlargement of the heart and reduces fluid retention.

Contra-indications
• Kidney disease
• Narrowed aortic valve in the heart
• Very low blood pressure

Side Effects
The most common side effects of these drugs are
• Dizziness / Light-headedness
• Dry persistent cough
• Skin rash (which may be associated with itch)
• Runny nose or taste disturbance
• A change in kidney function (checked by blood tests)

Please discuss with your GP or Heart Failure Nurse if experiencing any of these effects.

It is important that your blood pressure and kidney function are carefully monitored by the GP or Nurse when the dose of tablet is increased and at regular intervals in the long term.

Taken from the Heart Failure Newsletter No9