Sunderland sack Paolo Di Canio after 13 games
The 45-year-old Italian has won three of his 13 matches since being appointed in March and the Black Cats have one point from five games this season.
"An announcement will be made in due course regarding a permanent successor," read a club statement.
In the meantime, coach Kevin Ball will take charge of the first-team squad.
The statement added: "The club would like to place on record its thanks to Paolo and his staff and wishes them well for the future."
Ball's opening duty is to prepare the side for Tuesday's Capital One Cup third-round match against Peterborough United at the Stadium of Light.